購物車
幫助
021-54845833/15800441009
技術規(guī)格
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Background: |
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
LIFR |
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Immunogen: |
Synthetic peptide of human LIFR |
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Full name: |
leukemia inhibitory factor receptor alpha |
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Synonyms： |
SWS, SJS2, STWS, CD118, LIF-R |
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SwissProt: |
P42702 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human colon cancer and Human ovarian cancer |
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IHC Recommend dilution: |
25-100 |
