Name: 小鼠抗RUNX1T1單克隆抗體
Brand: 通蔚生物

中文名稱: 小鼠抗RUNX1T1單克隆抗體

英文名稱: Anti-RUNX1T1 mouse monoclonal antibody

別名: CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8

儲存: 冷凍（-20℃）避光

抗原: RUNX1T1

宿主: Mouse

反應(yīng)種屬: Human

相關(guān)類別: 一抗

標記物: Unconjugate

克隆類型: mouse monoclonal

技術(shù)規(guī)格

Background:	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Applications:	WB, IF
Name of antibody:	RUNX1T1
Immunogen:	Fusion protein of human RUNX1T1
Full name:	runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3
Synonyms:	CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8
SwissProt:	Q06455
WB Predicted band size:	68 kDa
WB Positive control:	Hela, SVT2, A549, COS7, Jurkat, PC12, MCF-7 cell lysates
WB Recommended dilution:	500-2000

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