購(gòu)物車(chē)
幫助
021-54845833/15800441009
技術(shù)規(guī)格
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Background: |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IF |
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Name of antibody: |
PDGFRB |
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Immunogen: |
Fusion protein of human PDGFRB |
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Full name: |
platelet-derived growth factor receptor, beta polypeptide (PDGFRB) |
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Synonyms: |
IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1 |
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SwissProt: |
P09619 |
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WB Predicted band size: |
124 kDa |
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WB Positive control: |
SVT2 cell lysate |
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WB Recommended dilution: |
500-2000 |
