購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：兔抗AIFM1多克隆抗體
英文名稱(chēng)： Anti-AIFM1 rabbit polyclonal antibody
別 名： AIF, PDCD8, COXPD6
儲(chǔ) 存： 冷凍（-20℃）
抗 原： AIFM1
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
技術(shù)規(guī)格
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Background: |
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
AIFM1 |
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Immunogen: |
Fusion protein of human AIFM1 |
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Full name: |
apoptosis-inducing factor, mitochondrion-associated, 1 |
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Synonyms： |
AIF, PDCD8, COXPD6 |
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SwissProt: |
O95831 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and human colon cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
67 kDa |
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WB Positive control: |
NIH/3T3 , Hela and 293T cells |
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WB Recommended dilution: |
500-2000 |
