Name: APLF 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：APLF 抗原（重組蛋白）

英文名稱： APLF Antigen (Recombinant Protein)

別名： aprataxin and PNKP like factor; APFL; PALF; Xip1; C2orf13

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human APLF

技術(shù)規(guī)格：

Full name:	aprataxin and PNKP like factor
Synonyms:	APFL; PALF; Xip1; C2orf13
Swissprot:	Q8IW19
Gene Accession:	BC041144
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

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