Name: BTK抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： BTK抗原（重組蛋白）

英文名稱： BTK Antigen (Recombinant Protein)

別名： Bruton tyrosine kinase; AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1

相關(guān)類別：抗原

儲存： 冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 460-659 amino acids of human BTK

技術(shù)規(guī)格

Full name:	Bruton tyrosine kinase
Synonyms:	AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1
Swissprot:	Q06187
Gene Accession:	BC109079
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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