Name: MMP13抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MMP13抗原（重組蛋白）

英文名稱： MMP13 Antigen (Recombinant Protein)

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述

Fusion protein corresponding to C terminal 350 amino acids of human MMP13

技術(shù)規(guī)格

Full name:	Matrix metalloproteinase-13
Synonyms:	CLG3, MANDP1
Swissprot:	P45452
Gene Accession:	BC067522
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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