購物車
幫助
021-54845833/15800441009
中文名稱：IL1B抗原（重組蛋白）
英文名稱： IL1B Antigen (Recombinant Protein)
別 名： IL-1; IL1F2; IL1-BETA
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別：抗原
概述
|
Fusion protein corresponding to a region derived from 1-269 amino acids of human IL1B |
|
Full name: |
interleukin 1 beta |
|
Synonyms: |
IL-1; IL1F2; IL1-BETA |
|
Swissprot: |
P01584 |
|
Gene Accession: |
BC008678 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
