購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗MCTS1多克隆抗體
英文名稱： Anti-MCTS1 rabbit polyclonal antibody
別 名： MCT1; MCT-1
相關(guān)類別： 一抗
抗 原： MCTS1
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MCTS1 |
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Immunogen: |
Fusion protein of human MCTS1 |
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Full name: |
malignant T cell amplified sequence 1 |
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Synonyms： |
MCT1; MCT-1 |
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SwissProt: |
Q9ULC4 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human colon cancer and human esophagus cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
21 kDa |
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WB Positive control: |
Jurkat and K562 cells, PC3 and A549 cells |
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WB Recommended dilution: |
200-1000 |
