Name: MDFI 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：MDFI 抗原（重組蛋白）

英文名稱： MDFI Antigen (Recombinant Protein)

別名： MyoD family inhibitor; I-MF; I-mfa

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 1-246 amino acids of human MDFI

技術規格：

Full name:	MyoD family inhibitor
Synonyms:	I-MF; I-mfa
Swissprot:	Q99750
Gene Accession:	BC007836
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

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