購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱： 兔抗GSTM4多克隆抗體
英文名稱： Anti-GSTM4 rabbit polyclonal antibody
別 名： GTM4; GSTM4-4
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
抗 原： GSTM4
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型：rabbit polyclonal
Background:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.
Applications:
ELISA, WB, IHC
Name of antibody:
GSTM4
Immunogen:
Full length fusion protein
Full name:
glutathione S-transferase mu 4
Synonyms：
GTM4; GSTM4-4
SwissProt:
Q03013
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer and human lung cancer
IHC Recommend dilution:
10-50
WB Predicted band size:
26 kDa
WB Positive control:
Mouse liver tissue，Mouse lung tissue
WB Recommended dilution:
200-1000
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