購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PTPRM多克隆抗體
英文名稱： Anti-PTPRM rabbit polyclonal antibody
別 名： RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PTPRM
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PTPRM |
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Immunogen: |
Synthetic peptide of human PTPRM |
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Full name: |
Protein tyrosine phosphatase, receptor type, M |
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Synonyms： |
RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU |
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SwissProt: |
P28827 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human breast cancer and Human lung cancer |
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IHC Recommend dilution: |
50-200 |
