中文名稱：兔抗FOS(Ab-232) 多克隆抗體

英文名稱： Anti-FOS(Ab-232) rabbit polyclonal antibody

別名： p55; AP-1; C-FOS

相關(guān)類別：一抗

抗原： FOS(Ab-232)

儲(chǔ) 存： 冷凍（-20℃）避光

宿主： Rabbit

反應(yīng)種屬： Human Mouse

標(biāo) 記物： Unconjugate

克隆類型： Unconjugate

技術(shù)規(guī)格

Background:

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

Applications:

WB

Name of antibody:

FOS(Ab-232)

Immunogen:

Synthesized non-phosphopeptide derived from human FOS around the phosphorylation site of threonine 232 (V-A-T(p)-P-E).

Full name:

FBJ murine osteosarcoma viral oncogene homolog

Synonyms：

p55; AP-1; C-FOS

SwissProt:

P01100

WB Predicted band size:

41 kDa

WB Positive control:

RAW264.7 cells lysate

WB Recommended dilution:

500-3000

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兔抗FOS(Ab-232) 多克隆抗體說明書
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兔抗FOS(Ab-232) 多克隆抗體

Background:	Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
Applications:	WB
Name of antibody:	FOS(Ab-232)
Immunogen:	Synthesized non-phosphopeptide derived from human FOS around the phosphorylation site of threonine 232 (V-A-T(p)-P-E).
Full name:	FBJ murine osteosarcoma viral oncogene homolog
Synonyms：	p55; AP-1; C-FOS
SwissProt:	P01100
WB Predicted band size:	41 kDa
WB Positive control:	RAW264.7 cells lysate
WB Recommended dilution:	500-3000