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021-54845833/15800441009
中文名稱(chēng)：兔抗SEMA4A多克隆抗體
英文名稱(chēng)： Anti-SEMA4A rabbit ployclonal antibody
別 名： RP35; SEMB; SEMAB; CORD10
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： SEMA4A
反應(yīng)種屬： Human
標(biāo)記物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SEMA4A |
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Immunogen: |
Fusion protein of human SEMA4A |
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Full name: |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
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Synonyms： |
RP35; SEMB; SEMAB; CORD10 |
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SwissProt: |
Q9H3S1 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer |
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IHC Recommend dilution: |
25-100 |
