購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗SLC22A17多克隆抗體
英文名稱(chēng)： Anti-SLC22A17 rabbit polyclonal antibody
別 名： BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： SLC22A17
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SLC22A17 |
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Immunogen: |
Synthetic peptide of human SLC22A17 |
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Full name: |
solute carrier family 22, member 17 |
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Synonyms： |
BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3 |
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SwissProt: |
Q8WUG5 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer and Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
56 kDa |
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WB Positive control: |
Human esophagus cancer tissue |
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WB Recommended dilution: |
500-2000 |
