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中文名稱： 兔抗PLA2G4A多克隆抗體
英文名稱： Anti-PLA2G4A rabbit polyclonal antibody
別 名： PLA2G4; cPLA2-alpha
相關(guān)類別： 一抗
抗 原： PLA2G4A
儲 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PLA2G4A |
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Immunogen: |
Fusion protein of human PLA2G4A |
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Full name: |
phospholipase A2, group IVA (cytosolic, calcium-dependent) |
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Synonyms： |
PLA2G4; cPLA2-alpha |
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SwissProt: |
P47712 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human brain |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
85 kDa |
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WB Positive control: |
293T cells |
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WB Recommended dilution: |
500-2000 |
