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021-54845833/15800441009
中文名稱(chēng)： 兔抗PSMD12多克隆抗體
英文名稱(chēng)： Anti-PSMD12 rabbit polyclonal antibody
別 名： proteasome 26S subunit, non-ATPase 12; p55; Rpn5; STISS
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PSMD12
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PSMD12 |
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Immunogen: |
Fusion protein of human PSMD12 |
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Full name: |
proteasome 26S subunit, non-ATPase 12 |
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Synonyms: |
p55; Rpn5; STISS |
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SwissProt: |
O00232 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer and Human tonsil |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
53 kDa |
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WB Positive control: |
Rat heart tissue lysate |
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WB Recommended dilution: |
500-2000 |
