中文名稱：兔抗TFEB多克隆抗體

英文名稱： Anti-TFEB rabbit polyclonal antibody

別名： transcription factor EB; TCFEB; BHLHE35; ALPHATFEB

相關(guān)類別：一抗

儲(chǔ) 存： 冷凍（-20℃）

宿主： Rabbit

抗原： TFEB

反應(yīng)種屬： Human, Mouse

標(biāo) 記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Regulates lysosomal positioning in response to nutrient deprivation by promoting the expression of PIP4P1 (PubMed:29146937).

Applications:

ELISA, IHC

Name of antibody:

TFEB

Immunogen:

Fusion protein of human TFEB

Full name:

transcription factor EB

Synonyms:

TCFEB; BHLHE35; ALPHATFEB

SwissProt:

P19484

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human gastric cancer

IHC Recommend dilution:

50-200

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兔抗TFEB多克隆抗體說明書
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021-54845833/15800441009

ELISA試劑盒

PCR試劑盒

生化試劑盒

細(xì)胞系

細(xì)胞庫

基礎(chǔ)培養(yǎng)基

完全培養(yǎng)基

原代細(xì)胞

細(xì)胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

標(biāo)準(zhǔn)品

血清

形態(tài)病理檢測(cè)

分子病理

超微病理

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兔抗TFEB多克隆抗體

Background:	Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta. Regulates lysosomal positioning in response to nutrient deprivation by promoting the expression of PIP4P1 (PubMed:29146937).
Applications:	ELISA, IHC
Name of antibody:	TFEB
Immunogen:	Fusion protein of human TFEB
Full name:	transcription factor EB
Synonyms:	TCFEB; BHLHE35; ALPHATFEB
SwissProt:	P19484
ELISA Recommended dilution:	5000-10000
IHC positive control:	Human tonsil and Human gastric cancer
IHC Recommend dilution:	50-200