購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗ARHGEF7多克隆抗體
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Background: |
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ARHGEF7 |
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Immunogen: |
Fusion protein of human ARHGEF7 |
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Full name: |
Rho guanine nucleotide exchange factor (GEF) 7 |
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Synonyms: |
P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314 |
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SwissProt: |
Q14155 |
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IHC positive control: |
Human gastric cancer and human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
90 kDa |
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WB Positive control: |
Human brain malignant glioma tissue, A172 and 293T cells |
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WB Recommended dilution: |
500-2000 |
