購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱：兔抗CCDC88A(Phospho-Ser1417)多克隆抗體
英文名稱： Anti-CCDC88A(Phospho-Ser1417) rabbit polyclonal antibody
別 名： APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
抗 原： CCDC88A(Phospho-Ser1417)
反應(yīng)種屬： Human Mouse
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： Unconjugate
技術(shù)規(guī)格
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Background: |
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Applications: |
IHC |
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Name of antibody: |
CCDC88A(Phospho-Ser1417) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin . |
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Full name: |
coiled-coil domain containing 88A |
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Synonyms： |
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212 |
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SwissProt: |
Q3V6T2 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
