中文名稱：兔抗HDAC5 (Phospho-Ser498)多克隆抗體

英文名稱： Anti-HDAC5 (Phospho-Ser498) rabbit polyclonal antibody

別名： HD5; NY-CO-9

相關(guān)類別：一抗

儲存： 冷凍（-20℃）避光

宿主： Rabbit

抗原： HDAC5 (Phospho-Ser498)

反應(yīng)種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術(shù)規(guī)格

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

WB, IHC

Name of antibody:

HDAC5 (Phospho-Ser498)

Immunogen:

Synthetic peptide of human HDAC5 (Phospho-Ser498)

Full name:

histone deacetylase 5 (Phospho-Ser498)

Synonyms：

HD5; NY-CO-9

SwissProt:

Q9UQL6

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

122 kDa

WB Positive control:

293 cells untreated or treated with serum starvation

WB Recommended dilution:

500-1000

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細胞專用培養(yǎng)基

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兔抗HDAC5 (Phospho-Ser498)多克隆抗體

Background:	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
Applications:	WB, IHC
Name of antibody:	HDAC5 (Phospho-Ser498)
Immunogen:	Synthetic peptide of human HDAC5 (Phospho-Ser498)
Full name:	histone deacetylase 5 (Phospho-Ser498)
Synonyms：	HD5; NY-CO-9
SwissProt:	Q9UQL6
IHC positive control:	Human breast carcinoma
IHC Recommend dilution:	50-100
WB Predicted band size:	122 kDa
WB Positive control:	293 cells untreated or treated with serum starvation
WB Recommended dilution:	500-1000