Name: DNTT 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：DNTT 抗原（重組蛋白）

英文名稱： DNTT Antigen (Recombinant Protein)

別名： DNA nucleotidylexotransferase; TDT

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 260-509 amino acids of human DNTT

技術(shù)規(guī)格：

Full name:	DNA nucleotidylexotransferase
Synonyms:	TDT
Swissprot:	P04053
Gene Accession:	BC012920
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

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