購物車
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021-54845833/15800441009
中文名稱 ： 兔抗PCP4多克隆抗體
英文名稱 ： Anti-PCP4 rabbit polyclonal antibody
別 名 ： PEP-19
相關(guān)類別 ： 一抗
抗 原 ： PCP4
儲(chǔ) 存 ： 冷凍（-20℃）
宿 主 ： Rabbit
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer’s disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
PCP4 |
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Immunogen: |
Fusion protein of human PCP4 |
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Full name: |
purkinje cell protein 4 |
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Synonyms： |
PEP-19 |
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SwissProt: |
P48539 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human cervical cancer and human tonsil |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
7 kDa |
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WB Positive control: |
Mouse brain tissue |
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WB Recommended dilution: |
500-2000 |
